Corticosteroid actions on amino acid-mediated transmission in rat CA1 hippocampal cells
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چکیده
منابع مشابه
Corticosteroid actions on amino acid-mediated transmission in rat CA1 hippocampal cells.
We here describe actions mediated by mineralo- and glucocorticoid receptors (MRs and GRs, respectively) on intracellularly recorded synaptic responses, evoked in rat CA1 pyramidal cells in vitro by stimulation of the Schaffer collaterals. Neurons in slices from adrenalectomized (ADX) rats, that is, where MRs and GRs are unoccupied, showed a synaptic response consisting of an EPSP, followed by a...
متن کاملThe effect of ketamine on NMDA receptor-mediated LTP depends on ketamine effects on non-NMDA-mediated synaptic transmission in CA1 area of rat hippocampal slices
It has been reported that ketamine as an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist has also non-NMDA receptor antagonist properties. We recently found that ketamine (20 ?M) affected differently induction of NMDA receptor-mediated long-term potentiation (LTP) when administered 30 min prior to tetanic Primed-Bursts (PBs) stimulation. On the other hand, ketamine also influenced...
متن کاملThe effect of ketamine on NMDA receptor-mediated LTP depends on ketamine effects on non-NMDA-mediated synaptic transmission in CA1 area of rat hippocampal slices
It has been reported that ketamine as an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist has also non-NMDA receptor antagonist properties. We recently found that ketamine (20 ?M) affected differently induction of NMDA receptor-mediated long-term potentiation (LTP) when administered 30 min prior to tetanic Primed-Bursts (PBs) stimulation. On the other hand, ketamine also influenced...
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متن کاملThe effect of ketamine on synaptic transmission and synaptic plasticity in CA1 area of rat hippocampal slices
The effect of ketamine (1-100 µM), which has NMDA receptor antagonist properties, on synaptic transmission and long-term potentiation (LTP) in CAl area of rat hippocampus was examined in vitro. Field potentials were recorded in pyramidal cell layer following Schaffer collateral stimulation. Primed-burst stimulation (PEs) was used for induction of LTP. The amplitude of population spiks (PS) was ...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1993
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.13-09-04082.1993